The anti-wrinkle treatment Dysport works better than its older, more popular rival, Botox, at least on certain parts of the face, researchers say.
The two drugs faced off in a recent study designed to figure out which drug could best smooth out crow's feet wrinkles that extend from around the eyes on the temples of the face. Participants had one side of their face injected with Dysport and the other with Botox.
Dysport proved superior at reducing signs of crow's feet wrinkles when participants contracted their facial muscles as much as they could. In addition, two-thirds of the participants preferred the results on the side of the face treated with Dysport. Neither the researchers nor the patients knew which side received which treatment.
Botox and Dysport contain a slightly different chemical variation of botulinum toxin, a protein made by the bacteria Clostridium botulinum. The drugs are thought to work in the same way, by blocking nerve signals to the muscles, thus relaxing them. Botox has been approved by the Food and Drug Administration for the treatment of wrinkles between the eyes (forehead wrinkles) in 2002, and Dysport was approved for the same use in 2009.
To test their effectiveness in smoothing out other wrinkles, the newest "split-face" research, headed by Dr Corey Maas, a plastic surgeon at San Francisco, Calif., involved 90 participants with a mean age of 54.
Doctors and patients were asked to rate the intensity of the crow's feet wrinkles on a scale of 0 (no wrinkles) to 4 (severe wrinkles), both in the time of the shot and one month later.
Depending on the scores, Dysport had an edge over Botox in reducing signs of wrinkles when patients contracted their muscles, as you might during grinning. When patients' muscles were at rest, there was not a significant gap between the scores.
The researchers used three times as much Dysport as they did Botox said Dr. Gary Monheit an associate clinical professor of dermatology at the University of Alabama at Birmingham, who wasn't involved in the work. Earlier studies conducted by the FDA used less Dysport, at a ratio of 2.5 to 1. Since either of these products will have a higher efficacy if the dose is increased, the researchers, if they intended to or not, might have"stacked the deck" in favour of Dysport, Monheit explained.
"A previous study that utilized a higher dose of Botox compared to one in this study found Botox was the better of the pair, '' he explained.
"For me, they're all nearly the same," he explained of the products. There's no established dose conversion between Botox or Dysport, according to a health expert.
It concludes that both have their respective benefits. The best solution is to choose the best skin care specialist for your treatments.
To get more personalized information, the best thing to do is schedule a consultation with Stacey Power at the Beautiphi Auckland.
Facebook: https://www.facebook.com/beautiphiNZ/
Youtube: https://www.youtube.com/channel/UCw3WRVVzRVt9D3In_iKrMYA/
Customer care: info@beautiphi.co.nz
Contact: 022 383 7968
The two drugs faced off in a recent study designed to figure out which drug could best smooth out crow's feet wrinkles that extend from around the eyes on the temples of the face. Participants had one side of their face injected with Dysport and the other with Botox.
Dysport proved superior at reducing signs of crow's feet wrinkles when participants contracted their facial muscles as much as they could. In addition, two-thirds of the participants preferred the results on the side of the face treated with Dysport. Neither the researchers nor the patients knew which side received which treatment.
Wrinkle Wars on Your Skin
Botox and Dysport contain a slightly different chemical variation of botulinum toxin, a protein made by the bacteria Clostridium botulinum. The drugs are thought to work in the same way, by blocking nerve signals to the muscles, thus relaxing them. Botox has been approved by the Food and Drug Administration for the treatment of wrinkles between the eyes (forehead wrinkles) in 2002, and Dysport was approved for the same use in 2009.
To test their effectiveness in smoothing out other wrinkles, the newest "split-face" research, headed by Dr Corey Maas, a plastic surgeon at San Francisco, Calif., involved 90 participants with a mean age of 54.
Doctors and patients were asked to rate the intensity of the crow's feet wrinkles on a scale of 0 (no wrinkles) to 4 (severe wrinkles), both in the time of the shot and one month later.
Depending on the scores, Dysport had an edge over Botox in reducing signs of wrinkles when patients contracted their muscles, as you might during grinning. When patients' muscles were at rest, there was not a significant gap between the scores.
Dosage issue
The researchers used three times as much Dysport as they did Botox said Dr. Gary Monheit an associate clinical professor of dermatology at the University of Alabama at Birmingham, who wasn't involved in the work. Earlier studies conducted by the FDA used less Dysport, at a ratio of 2.5 to 1. Since either of these products will have a higher efficacy if the dose is increased, the researchers, if they intended to or not, might have"stacked the deck" in favour of Dysport, Monheit explained.
"A previous study that utilized a higher dose of Botox compared to one in this study found Botox was the better of the pair, '' he explained.
"For me, they're all nearly the same," he explained of the products. There's no established dose conversion between Botox or Dysport, according to a health expert.
It concludes that both have their respective benefits. The best solution is to choose the best skin care specialist for your treatments.
To get more personalized information, the best thing to do is schedule a consultation with Stacey Power at the Beautiphi Auckland.
Address: Beautiphi, 2C/1, Tika Street, Parnell, Auckland, 1052, New Zealand
Website: https://www.beautiphi.co.nz/
Website: https://www.beautiphi.co.nz/
Facebook: https://www.facebook.com/beautiphiNZ/
Youtube: https://www.youtube.com/channel/UCw3WRVVzRVt9D3In_iKrMYA/
Customer care: info@beautiphi.co.nz
Contact: 022 383 7968
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